Sheriff Larry Amerson said the victims told deputies that the home had been broken into twice since Aug. 8, but they did not feel the need to report the first incident.
The victims told deputies that they believed the suspects entered the home through a rear window, but investigators found no sign of forced entry, Amerson said.
Among the items stolen were a water heater, an arrowhead collection, a wheelbarrow, a cedar chest, a lawnmower engine, several silver coins and an antique sewing machine.
Amerson said the original homeowners died 10 years ago, and ownership of the home on Halls Mill Road is now split among their children.
Any suspect who could face felony charges of third-degree burglary.
Staff writer Madasyn Czebiniak: 256-235-3546. On Twitter @MCzebiniak_Star.